Hadi Mirahmadi - Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute & Department of Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Ahmad Mehravaran - Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute & Department of Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Masoumeh sani Haidari - ۲. Department of Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Mansour Rahmati-Balaghaleh - Department of Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Vahid Raissi - Department of Medical Parasitology and Mycology, Faculty of public health, Tehran University of Medical Sciences, Tehran, Iran
Reza shafiei - Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran

Background: Toxoplasma gondii is one of the most prevalent zoonotic opportunistic parasitic infections in the world. The aim of this study was to examine chronic and acute toxoplasmosis molecularly and serologically in Hemodialysis patients.Methods: A total of ۲۳۸ serum samples of hemodialysis patients with chronic renal disease (۱۱۹ samples) as case group and healthy individuals (۱۱۹ samples) as control group were enrolled in Zahedan City, southeastern Iran. The molecular and serological detection of toxoplasmosis were conducted on all samples using nested-PCR and ELISA.Results: The prevalence rates of anti-T. gondii IgM and IgG and T. gondii DNA in the case group were respectively ۰%, ۴۴.۵% and ۲۹.۴% and the corresponding values in the control group were ۰.۸%,۲۳.۵% and ۲.۵۲ % respectively (p≥۰.۰۵).Conclusion: In conclusion, preliminary Toxoplasma gondii infection screening is required using serological techniques, particularly in hemodialysis patients who are frequently exposed to hemodialysis so as to stop infection dissemination.

Toxoplasma, Hemodialysis patients, Nested-PCR, Zahedan