C-reactive protein and Platelets changes in preterm neonates with patent Ductus Arteriosus

Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JKMU-26-4_001

تاریخ نمایه سازی: 19 دی 1401

Abstract:

Introduction: This study aimed to investigate CRP and platelet count changes in preterm neonates with Patent Ductus Arteriosus on the seventh day of birth compared to the third day. Methods: This longitudinal study was conducted on fifty neonates with PDA complications in Afzalipour hospital in ۲۰۱۷-۲۰۱۸. All neonates underwent repeated echocardiography before the closure of their arterial duct and ۲ cc of blood sample was taken from each neonate and was sent to the laboratory for platelet and CRP count test. Result: The mean of platelet was ۲۹۶.۱۷±۱۸.۰۸ on day ۷, and it was significantly different compared to day ۳ (۱۹۵.۴۹ ± ۱۰.۴۹). The arterial ducts of ۱۵ neonates out of ۵۰ patients with PDA were closed on the seventh day. The mean of CRP was significantly different in neonates with PDA (۳۵.۷۰) compared to neonates with closed arterial ducts (۲.۳۲) on day ۷. Conclusions: The results of this study revealed that PDA is associated with a low number of platelets and high level of CRP in preterm neonates.

Authors

Mohammad Mahdi Bagheri

Assistant Professor, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran

Homa Ghabeli

Afzalipour Medical Center, Kerman University of Medical Sciences, Kerman, Iran

Pedram Niknafs

Professor, Department of Pediatrics, Kerman University of Medical Sciences, Kerman, Iran

Saeedeh Parvaresh

Assistant Professor, Department of Pediatrics, Kerman University of Medical Sciences, Kerman, Iran

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