Fatemeh Safavi - Student of Dentistry, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
Gholamreza Yousefzadeh - Assistant Professor, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
Mostafa Shokoohi - Researcher, Research Center for Modeling in health, Institute for Future Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
Sadaf Safavi - General Practitioner, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
Hamid Najafipour - Professor, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
Mitra Shadkam Farokhi - Research assistant, Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran

Background & Aims: Metabolic syndrome is composed of interrelated cardiovascular and cardiometabolic risk factors. Moreover, recent researches have illustrated the association of systemic diseases and periodontitis. Thus, the early diagnosis of this syndrome, as a cardiometabolic risk factor, seems necessary. The aim of this study was to evaluate the prevalence of metabolic syndrome in patients with periodontal disease. Methods: In this cross-sectional study, ۹۰۰ subjects from the data bank of the Kerman Coronary Artery Disease Risk Study (KERCADRS), Iran, were assessed. The community periodontal index (CPI) was used as the evaluation tool for periodontal treatment needs and health condition . The control group consisted of healthy individuals. Results: The prevalence of metabolic syndrome among patients with periodontal disease was significantly higher than the healthy group (۵۳.۶% vs. ۳۳.۱%, P < ۰.۰۰۱). High waist circumference, triglyceride disorder, high fasting blood sugar (FBS), and high blood pressure were significantly higher in patients with periodontal disease (P < ۰.۰۵). After controlling the effect of confounding variables (age, gender and BMI), the adjusted odds ratio of existence of periodontal pockets were ۱.۵۸ (۹۵% CI: ۱.۱-۲.۲, P = ۰.۰۱۲) for metabolic syndrome patients. Conclusion: Our results showed a high prevalence of cardiovascular disease risk factors among patients with periodontal disease. Therefore, screening these patients for cardiovascular disease risk factors is suggested.

Metabolic Syndrome, Periodontal disease, Cardiovascular Diseases, risk factors, Iran