Survival in Nonmetastatic Gastric Cancer Patients

Background & Aims: Gastric carcinoma is the second most frequent cancer worldwide. Adjuvant treatment of gastric cancer varies worldwide; many differences have been observed in their clinical and pathological features, and survival rate. The aim of this study was to determine clinical and pathological features, and survival rate in a group of patients in south-east of Iran. Methods: Patient records and pathological reports of ۸۲ consecutive patients, with nonmetastatic gastric cancer referring to the radiation oncology ward of Kerman Shafa Hospital since September ۲۰۰۳ to October ۲۰۱۱, were studied. Survival rate was estimated by the Kaplan-Meier method and differences in survival curves between the variables were determined by logrank test. Results: The mean age of the subjects was ۵۲ years and the male to female ratio was ۱.۸:۱. Surgery with positive microscopic margin was performed in ۱۹ patients (۲۳.۲%). The number (%) of the patients with stage I, II, III, and IV were ۷ (۸.۵%), ۲۱ (۲۵.۶%), ۳۵ (۴۲.۷%), and ۱۹ (۲۳.۲%), respectively. The ۲ years and ۵ years survival rates were ۲۲% and ۵۳%, respectively. Only T, N, overall stage, and type of surgery had impact on the survival rate (P < ۰.۰۵), and the other variables had no significant roles. Conclusion: Gastric cancer continues to present in advanced stages, with poor prognosis. The findings of this study emphasize the need for employing policies for the early detection of gastric cancer.

Keywords:

Gastric cancer , Chemotherapy , radiotherapy , survival