Khatera Wahedi - Faculty of Chemistry, Bu-Ali Sina University, Hamedan ۶۵۱۷۸-۳۸۶۸۳, Iran
Parvaneh Amooshahi - Faculty of Chemistry, Bu-Ali Sina University, Hamedan ۶۵۱۷۸-۳۸۶۸۳, Iran
Mahdi Jamshidi - Department of Toxicology and Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran
Sadegh Khazalpour - Faculty of Chemistry, Bu-Ali Sina University, Hamedan ۶۵۱۷۸-۳۸۶۸۳, Iran

In this work, electrochemical behavior of Caffeic Acid (CA) in absence and presence of aromatic amines such as ۴-amino-۱,۳-Dimethyluracil (۴A-DMU), p-toluidine (p-TI), and Sulfacetamide (SA) have been performed by cyclic voltammetry technique in water (sodium acetate, c = ۰.۱۵ M)/ethanol (۸۰:۲۰, v/v) mixture. In this way, the effect of different parameters such as concentration and scan rate indicated that the oxidation mechanism of caffeic acid (CA) in the presence of aromatic amines can be EC and ECE. At the working electrode surface, Caffeic Acid (CA) oxidized to correponding o-benzoquinone (CAOX) with two electrons and two protons process. In the following, the Michael-type addition reaction has occurred between o-benzoquinone and aromatic amines. In the second cycle, a new oxidation peak appears in negative potentials than Caffeic Acid (CA) oxidation peak because of the electron-donating properties of amines. Cyclic voltammetry technique can recognize chemical and electrochemical processes in solution and electrode surface, respectively.

Electrochemical behavior, Cyclic Voltammetry, Green chemistry, caffeic acid, Aromatic amines, ECE mechanism