Prevalence of Class ۱ Integron in Klebsiella Pneumoniae Isolates from Hospitals of Sanandaj, Iran
عنوان مقاله: Prevalence of Class ۱ Integron in Klebsiella Pneumoniae Isolates from Hospitals of Sanandaj, Iran
شناسه ملی مقاله: JR_JIML-7-1_006
منتشر شده در در سال 1398
شناسه ملی مقاله: JR_JIML-7-1_006
منتشر شده در در سال 1398
مشخصات نویسندگان مقاله:
پگاه شکیب - Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
خلاصه مقاله:
پگاه شکیب - Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Background and Aims: Integrons as mobile genetic elements are located on the chromosome or on a plasmid in bacteria. Integrons play a main role in the dissemination of antibiotic resistance genes among different families of bacteria. The aim of this study was to identify the prevalence of class ۱ integron in Klebsiella pneumoniae isolates from hospitals of Sanandaj, Kurdistan province, Iran.
Materials and Methods: Seventy Klebsiella pneumoniae isolates were collected from Hospitals of Sanandaj. Antibiotic susceptibility pattern was performed by disc diffusion method. Class ۱ integrons gene was screened by polymerase chain reaction assay. Data were analyzed by Fisher tests with STATA software program.
Results: The highest and lowest rates of resistance were related to cefotaxime and imipenem, respectively. Thirteen (۱۸.۵%) out of ۷۰ Klebsiella pneumoniae isolates caring class ۱ integron gene. Out of ۲۸ multidrug resistant isolates, ۱۱ isolates were identified to be positive for the existence of class ۱ integrons.
Conclusions: class ۱ integron positive isolates, compared to class ۱ integron negative isolates, reveals resistance to more antibiotics.
کلمات کلیدی: Class ۱ Integron, Klebsiella pneumoniae, PCR assay, Class ۱ Integron, Klebsiella pneumoniae, disc diffusion method, PCR assay
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1608809/