Vahid Mahmoudi - Department of Polymer and Textile Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
Saeid Jafari - Center for Growth of Technology, Knowledge based Nano Kimia Kavir Yazd Pharmaceutical co., Islamic Azad University, Yazd Branch, Yazd, IRAN

With the emergence of the industrial age, the growing concern over environmental pollution has been to drug resistance in humans due to the use of antibiotics and their discharge in environment. The aim of this work was to synthesis of a carbon ceramic composite based on molecular imprinted polymers (MIP) particles via non-covalent procedure as selective adsorbent for removal of Cloxacillin (CLO) antibiotic from aqueous and biological media (MILK). The effect of operational parameters includes pH (۳-۱۰), contact time (۱-۱۲۰ min), MIP (۰.۱ – ۵.۰ %wt) and adsorbent dosage (۰.۱- ۲.۰ g/L) was studied for optimization of CLO removal condition. The synthesized MIP particles and fabricated carbon composites were characterized using scanning electron microscopy and nitrogen absorption/desorption (BET). The results showed that the removal efficiency was highest in neutral conditions and increased as amount of MIP particles increased. The optimum conditions for removal of CLO (۹۴%) were determined at pH = ۶.۵, ۸۷ minutes as contact time and the ۱.۶ g/L carbon composite contain ۳.۱ % wt MIP. The performance of the synthesized composites was evaluated for Cloxacillin removal from the milk sample. The performance of the MIP particles for the Cloxacillin removal of milk samples supplied from livestock showed that these adsorbents can help to effectively reduce the residues of drug contamination in dairy samples.

Molecularly Imprinted Polymer, carbon ceramic composite, Cloxacillin, Milk