Ali Saffaei - Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Narges Sadat Zahed - Department of Nephrology, Shahid Beheshti University, Loghman-Hakim Hospital, Tehran, Iran.
Shahin Shadnia - Toxicology Research Center, Excellence Center of Clinical Toxicology AND Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Peyman Erfantalab - Toxicological Research Center, Department of Clinical Toxicology, Shahid Beheshti University of Medical Sciences, Loghman Hakim Hospital, Tehran, Iran.
Mitra Rahimi - Shahid Beheshti University of Medical Sciences

Introduction: Aluminum phosphide (AlP) is an effective fumigant and rodenticide which is a commonly used agent for suicide in parts of developing countries. AlP poisoning results in serious manifestations involving many vital organs and it has high mortality. Electrolyte and metabolic abnormalities including metabolic acidosis is a common problem in AlP poisoning. Case report: Here, we report two cases of AlP poisoning who take AlP tablets intentionally. The therapeutic intervention initiated for both of them including glucose, insulin, and potassium (GIK) protocol, antioxidants agents, intravenous magnesium, intravenous calcium, and norepinephrine. The arterial blood samples obtained in a serial manner and interestingly it showed no abnormality.Conclusion: This is first cases of AlP poisoning with normal acid base balance which emphasis the importance the early initiation of therapeutic intervention

Aluminum phosphide, Acidosis, Poisoning, Toxicity, blood gas