Effect of Smoking and Type of Nutrition on the Activity of Liver Alanine Aminotransferase and Aspartate Aminotransferase

Background: A healthy diet provides the body with essential nutrition that includes fluids,macronutrients, micronutrients, and calories. The liver is one of the most important organs in thebody that has the function of detoxification and cleansing, and smoking causes an additional burdenfor the detoxification function of the liver, which can lead to inflammation and fatty liver. This studywas designed to investigate the effects of smoking on liver function.Materials and Methods: This cross-sectional descriptive-analytical study investigated the relationshipbetween smoking and the type of nutrition of liver enzymes in healthy people and people whosmoke in Zabol. In this study, ۱۵۰ people were selected who were divided into two groups ofhealthy people without smoking (n=۷۵) and people with smoking with liver problems (n=۷۵).Results: There was no statistical relationship between age and levels of aspartate aminotransferase(AST) and alanine aminotransferase (ALT) liver enzymes (P>۰.۰۵). However, a relationship wasfound between weight and levels of liver enzymes AST and ALT. Hepatitis also increased (P<۰.۰۵),and there was a statistical relationship between alcohol consumption with AST and ALT liverenzymes; more precisely, the more alcohol consumption, the higher the amount of liver enzymes(P<۰.۰۵). Finally, no statistically significant relationship was observed between fruit and vegetableconsumption, rice consumption, meat consumption, and water consumption (P>۰.۰۵).Conclusion: This relationship is positive and direct; in other words, the higher the consumption oftobacco, the higher the activity of liver enzymes ALT and AST

Keywords:

Smoking , Liver Enzymes , Type of nutrition , Alanine aminotransferase , Aspartate aminotransferase