Mohammad Reza Mosaddegh - Clinical Supervisor, Dr. Sheikh Children&#۰۳۹;s Hospital, Mashhad University of Medical Sciences, Iran
Ali Ghasemi - Pediatric Hematology and Oncology Specialist, Assistant Professor, Department of Pediatrics, Dr. Sheikh Hospital, Mashhad University of Medical Sciences, Iran
Zahra Sepehri - Infection Control Supervisor, Dr. Sheikh Children&#۰۳۹;s Hospital, Mashhad University of Medical Sciences, Iran
Mojgan Bahari - Nursing manager, Dr. Sheikh Children&#۰۳۹;s Hospital, Mashhad University of Medical Sciences, Iran
Mahdi Jahangiri - Internist, Medical school, Mashhad University of Medical Sciences, Iran
Sara Jahangiri - Master of Nursing, Dr. Sheikh Children&#۰۳۹;s Hospital, Mashhad University of Medical Sciences, Iran

Background: Contamination of medical equipment and environmental surfaces with microorganisms plays a significant role in the transmission and spread of hospital infections. Considering the deaths and costs caused by hospital infections, it is necessary to take appropriate measures to prevent the spread of infection, such as cleaning and disinfection. The purpose of this study was determining the status of hospital infections before and after using the air and surface disinfectant device known as nocospray which applies dry mist technology and hydrogen peroxide solution.Method: This cross-sectional study was conducted in two ۶-month periods at Dr. Sheikh Children's Hospital, in Mashhad, between ۲۰۲۱ and ۲۰۲۲. All patients who were hospitalized for more than ۴۸ hours and had a hospital infection were included in the study. In the second ۶ months, a Nocospray disinfection device was used to disinfect surfaces and equipment. Nosocomial infection was determined according to clinical symptoms and blood, urine and tracheal tube cultures in both ۶-month periods and the results of the two periods were compared.Results: A total of ۱۹۸ cases of nosocomial infections were observed, ۱۲۱ cases (۶۱%) of which were related to the first ۶ months. The death rate in the second ۶ months decreased by ۱.۶۵% compared to the first ۶ months. Among children of different ages, the age range of ۱ to ۴ years accounted for the highest number of hospital infections. And the highest rate of infection was related to the intensive care unit.Conclusion: This study showed the positive effect of surface and air disinfection devices (Nocospray) in reducing the incidence of hospital infections and mortality.

Hospital acquired infection,,, ,،disinfection,,, ,،nocospray