Raad Muslim Muhiebes - Department of Biochemistry, College of Medicine, Missan University, Missan, Iraq
Leila Fatolahi - Department of Chemistry, Payame Noor University, PO BOX ۱۹۳۹۵-۴۶۹۷ Tehran, Iran
Sami Sajjadifar - Department of Chemistry, Payame Noor University, PO BOX ۱۹۳۹۵-۴۶۹۷ Tehran, Iran

In this study, L-Proline as an organo-catalyst has been used for the synthesis of highly functionalized tetrahydropyridines derivatives in good to excellent yields by one-pot multicomponent reaction (MCR) of aniline, methyl acetoacetate, and aromatic aldehydes in ethanol under reflux conditions. The use of green solvents, eco friendliness, mild reaction conditions, and low catalyst loading are advantages of current study.

L, Proline Tetrahydropyridines derivatives MCRs Organo, Catalyst