Seyed Majid Fatahi - Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
Sayyad Khanizadeh - Department of Virology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
Ali Safarzadeh - Department of Biology, University of Padova, Padova, Italy
Ashkan Alamdary - Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
Hadi Razavi Nikoo - Infectious Disease Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Rasool Mohammadi - Department of Biostatistics and Epidemiology, School of Public Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran
Annahita Ghalandarian - Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
Mehdi Ajorloo - Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran

Background and Aim: The novel coronavirus ۲۰۱۹ can lead to a vast range of respiratory complications, from mild to severe, driving to acute respiratory distress syndrome (ARDS). Common symptoms of COVID-۱۹ include fever, fatigue, and dry cough, which can lead to complications, such as gastrointestinal disorders, and liver, cardiac, and renal dysfunctions. Alteration in the hematological markers is one of the COVID-۱۹ diseases evaluated by our study. Materials and Methods: In this study, hematological markers, including the levels of ESR, BS, Hb, HCT, MCV, MCH, MCHC, platelet, WBC, RBC, neutrophil, and lymphocyte, have been assessed and compared in both case and control groups. Furthermore, we assessed the associations between hematological parameters, clinical manifestations, and underlying medical conditions. Results: Our data showed that RBC, HCT, and ESR were significantly associated with the novel coronavirus ۲۰۱۹ infection according to the disease progression. ESR (P= ۰.۰۲۲), Hb (P= ۰.۰۳۲), and BS (P= ۰.۰۱) levels in male people infected by SARS-CoV-۲ proved to have a significant relationship with the control group. Moreover, BS, Hb, HCT, ESR, and neutrophil showed significant variations in diabetic individuals suffering from SARS-CoV-۲ infection. Conclusion: The dropping of the hematological markers in COVID-۱۹ is linked with a noticeably increased mortality rate, while high neutrophil and BS levels are related to aggravation of the disease. Monitoring the hematological markers can contribute significantly to selecting the proper treatment and hamper of disease worsening.

COVID-۱۹, SARS-CoV-۲, Hematological, Marker, کووید-۱۹, سارس-کوو-۲, خونی, مارکر