Ali Reza Arabestanino - Harvard Medical School and Beth Israel Dissection Medical Center
Sina Naghibi Irvani - Harvard Medical School and Beth Israel Dissection Medical Centerl
Bita Dinarvand - Iran University of Medical Sciences, Tehran, Iran
Shirin Sabohi Moghadam - Iran University of Medical Sciences, Tehran, Iran
Arman Ai - Toronto Medical University

Introduction: Management of brainstem metastatic tumor is challenging. brainstem metastasis is an uncommon complication of systemic cancer, generally considered to have a highly unfavorable prognosis. Surgical risks are high and standard radiation or chemotherapy have little effect. The purpose of this study is to evaluate our experience an overview of the removal of abnormalities of brain stem metastases and the general treatment protocol of these types of metastases, which are very unfavorable.Methods: The present paper is a literature review using the following databases: PubMed, Scientific Direct, Library Genesis, using the terms: Brainstem Metastases Malformation. Articles from May ۲۰۱۹ were selected, resulting in a total of ۱۹ articles that met the inclusion criteria considering their citations and respective impacts.Results: Complications were predicted and observed according to existing factors and factors that will arise in the future. Local tumor control was achieved in ۹۰.۷% of patients.Conclusion: The results of this small series demonstrate that treatments now can be a valuable modality for safe and effective management of brain stem metastasis. Owing to the high risk of surgical resection and low efficacy of medical treatment, radiosurgery can be proposed upfront

Brainstem Metastatic, radiosurgery, Systemic Cancer, Chemotherapy, Abnormalities