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Exploring Factors Influencing the Efficacy of Dual Therapy in Gonorrhea Treatment: A Retrospective Study

عنوان مقاله: Exploring Factors Influencing the Efficacy of Dual Therapy in Gonorrhea Treatment: A Retrospective Study
شناسه ملی مقاله: JR_JMCH-6-11_004
منتشر شده در در سال 1402
مشخصات نویسندگان مقاله:

Hamidah Luthfidyaningrum - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Afif Nurul Hidayati - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Damayanti Damayanti - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Muhammad Yulianto Listiawan - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Cita Rosita Sigit Prakoeswa - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Linda Astari - Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Public Academic Teaching Hospital, Surabaya, Indonesia
Budi Utomo - Department of Public Health Sciences, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

خلاصه مقاله:
Background: Gonorrhea infection (GO) has a high prevalence in Indonesia, making it a significant public health concern. Effective treatment is crucial in controlling GO. However, the development of resistance has limited treatment options. Current guidelines recommend dual therapy as a syndromic approach. Treatment failures often result from a reinfection due to the barriers to therapy with sexual partners or engaging in sexual activity with newly infected partners. To prevent resistance and control its spread, transmission needs to be minimized. Various factors are associated with recovery as part of a comprehensive resistance control strategy, including appropriate medication, therapy adherence, sexual abstinence during treatment, and regular monitoring. Methods: This study utilized a retrospective cross-sectional design, analyzing medical records of Gonorrhea patients from the Sexually Transmitted Infections (STI) Outpatient Clinic, Dermatology, and Venereology Department, Dr. Soetomo Public Academic Teaching Hospital, Surabaya, between ۲۰۱۷ and ۲۰۲۱.Results: Out of ۱۰۹ GO patients, ۶۴ met the inclusion criteria. The analysis revealed a significant association between dual therapy cure for Gonorrhea and sexual abstinence (p-value = ۰.۰۰۱

کلمات کلیدی:
Gonorrhea Antibiotic resistance Sexual abstinence Sexually, transmitted disease

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1706848/