Sara Darvish - Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran.
Mohammar Reza Khataminejad - Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran.

Background and Objectives: Helicobacter pylori is the main etiology of peptic ulcers and chronic gastritis. The prevalence of Helicobacter pylori is typically higher in developing countries. The aim of this study was to determine the Prevalence compare of the invasive pathological method and serological diagnosis of Helicobacter pylori in patients at Taleghani hospital in Chalous from ۲۰۱۴- ۲۰۱۵ Materials and Methods: This study was performed on ۳۵۸ patients who referred to Taleghani Hospital Branch from ۲۰۱۴ to ۲۰۱۵. For detection of H. pylori the gastric antrum and duodenal biopsies were done by pathological method and determine of the Antibody (IgG) were done by ELISA method. Results and Conclusion: the results showed that the overall prevalence of H. pylori infection was ۲۲.۳۴% (۸۰/۳۵۸) and it was significantly higher in woman (۳۰.۰۶%) compared to man (۱۵.۸۹%) (p=۰.۰۰۱). The most prevalence was seen in ۲۶-۳۵ age group (۳۰.۸) and ۷۱-۸۰ weight group (۳۶.۱). The high prevalence of infection in the age group ۳۵-۲۶ years (۳۰.۸%), showed biopsy sampling of tissue staining is useful than serological test. This study showed that antibody titration alone is not sufficient for definitive diagnosis requires a biopsy is invasive sampling.

Prevalence, Helicobacter pylori, Biopsy, Serology, Chalous, شیوع, هلیکوباکتر پیلوری, بیوپسی, IgG, چالوس