Zahra khorasanchi - Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Vahedifard - Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran
Kimia Mohammadhasani - Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran
Yasamin Sharifan - Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra Dehnavi - Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ramtin Naderian - Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali Jafarzadeh Esfehani - Metabolic Syndrome Research Center. Mashhad University of Medical Sciences, Mashhad, Iran.
Payam Sharifan - Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Reza Zare-Feyzabadi - ۵International UNESCO Center for Health Related Basic Sciences and Human Nutrition, Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon A. Ferns - Department of Medical Education, Brighton and Sussex Medical School, Falmer, Brighton, UK.
Majid Ghayour - Biochemistry and Nutrition Research Center and Department of clinical biochemistry, Mashhad University of Medical Sciences, Mashhad, Iran

Introduction: The pandemic of COVID-۱۹ created a psychological response. So, the psychological function of COVID-۱۹ patients is an important subject that forces us to follow up with them.Aim: Assess the correlation between vitamin D serum concentrations and psychological functions such as insomnia, stress, and depression through the COVID-۱۹ pandemicMethods: In this cross-sectional study, blood samples from ۱۲۰ COVID-۱۹ patients (۶۱ males and ۵۹ females) who had more than ۳۰ years, were taken. Also, ۲۵(OH)D Serum level of COVID-۱۹ patients was analyzed. The Insomnia Severity Index (ISI), Depression anxiety stress scales (DASS), and the Short Form Health Survey (SF-۳۶) were used to analyze insomnia, anxiety, stress, quality of life, and depression.Results: The relationship between temperature (p=۰.۰۳۹), PCO۲ (p=۰.۰۲۲), and serum vitamin D level was significant. Additionally, there was a significant correlation between stress (p=-۰.۰۲۳, OR=۰.۳۸۹, ۹۵% CI for OR=۰.۰۴۷, ۰.۸۴۳), depression (p=۰.۰۱۲, OR=۰.۶۵۹, ۹۵% CI for OR=۰.۴۷۶, ۰.۹۱۳), and the concentration of serum vitamin D.Conclusion:This study recommends that vitamin D supplementation improve psychological state in COVID-۱۹ patients.

Vitamin D, COVID-۱۹, psychological function, Depression, stress