Determination of Dosimetric Parameters of the Second Model of Pd-۱۰۳ Seed Manufactured at Agricultural, Medical and Industrial Research School
عنوان مقاله: Determination of Dosimetric Parameters of the Second Model of Pd-۱۰۳ Seed Manufactured at Agricultural, Medical and Industrial Research School
شناسه ملی مقاله: JR_IJMP-5-1_002
منتشر شده در در سال 1387
شناسه ملی مقاله: JR_IJMP-5-1_002
منتشر شده در در سال 1387
مشخصات نویسندگان مقاله:
Gholamreza Raisali - Associate Professor, Radiation Application Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Tehran, Iran
Mahdi Sadeghi - Assistant Professor, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
Vahideh Ataeinia - M. Sc. in Medical Applications of Radiation, Nuclear Engineering Dept, Faculty of Engineering, Science and Research Unit, Islamic Azad University, Tehran, Iran
Arjang Shahvar - B. Sc. in Physics, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
Maryam Ghasemi Ghonchehnazi - M. Sc. in Medical Physics, Medical Physics Dept., Faculty of Medical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
خلاصه مقاله:
Gholamreza Raisali - Associate Professor, Radiation Application Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Tehran, Iran
Mahdi Sadeghi - Assistant Professor, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
Vahideh Ataeinia - M. Sc. in Medical Applications of Radiation, Nuclear Engineering Dept, Faculty of Engineering, Science and Research Unit, Islamic Azad University, Tehran, Iran
Arjang Shahvar - B. Sc. in Physics, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
Maryam Ghasemi Ghonchehnazi - M. Sc. in Medical Physics, Medical Physics Dept., Faculty of Medical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
Introduction: The use of low energy isotopes such as ۱۰۳ Pd in brachytherapy for the treatment of cancers such as prostate, eye, head, neck, breast and cervix is increasing. In this regard, different models of Pd- ۱۰۳ seeds have been designed and manufactured at the Agricultural, Medical and Industrial Research School (AMIRS) of Atomic Energy Organization of Iran. In this research, the dosimetric parameters of the second model of Pd-۱۰۳ seed manufactured at AMIRS have been calculated and measured. Materials and Methods: The dosimetric parameters of the second Pd-۱۰۳ seed manufactured at AMIRS were determined according to TG-۴۳U۱ protocol using Monte Carlo calculations (MCNP۴C computer code) and measurements performed using TLD-GR۲۰۰A dosimeters in a Perspex phantom. The parameters include dose rate constant, geometry function, radial dose function, anisotropy function, anisotropy factor and anisotropy constant. Results: It was found that by using MCNP۴C code the calculated dose rate constant in water and Perspex was ۰.۷۰۶±۰.۰۰۱ and ۰.۵۰۱±۰.۰۰۱ cGyh -۱ U -۱ , respectively. Using the calculated geometry function, the radial dose function and the anisotropy function were determined by experimental and theoretical methods in water and Perspex phantom. Also, the calculated value of anisotropy constant in water was equal to ۰.۸۸. Discussion and Conclusion: A discrepancy of less than ۱۰% between the calculated and the measured values indicates a reasonable agreement between the simulation and the measurement method. Also, the dosimetric parameters of this seed have been compared to the dosimetric parameters of the first Pd-۱۰۳ seed manufactured at AMIRS and some other seeds. The obtained results indicate that the seeds manufactured at AMIRS have acceptable dosimetric parameters suitable for brachytherapy applications.
کلمات کلیدی: Brachytherapy, Pd-۱۰۳ Seed, TG-۴۳U۱ Protocol, Monte Carlo Simulation, Thermoluminescent Dosimetry
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1739032/