Rakesh Ranjan Chakraborty - Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, India
Pranab Ghosh - Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, India

A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.

Nitriles, Aldehydes, Hydroxylaminehydrochloride, Silica-gel