Narjes Alamolhodaei - Department of Chemistry, Payame Noor University, Mashhad, Iran
Hossein Eshghi - Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad
Hossein Massoudi - department of chemistry, payame noor university, Tehran, I.R. Iran

Three components one-pot Mannich reaction of ketone, aromatic aldehyde and aromatic amines has been efficiently catalyzed by recyclable and heterogeneous L-Cysteine supported on ZnS nanoparticles at ambient temperature to give various β-amino carbonyl compounds with high yields. This simple method has some advantages such as mild condition and no environmental pollution. Structures of the compounds were confirmed by ۱H NMR and IR spectral analyses. ZnS nanoparticles were prepared in hydrothermal procedure from an aqueous solution of Zinc acetate and NaS in the presence of L-Cysteine. L-Cysteine supported on ZnS nanoparticles was characterized by FT-IR, TEM, TGA/DTA and XRD analysis.

Mannich, L-cysteine, Functionalized ZnS, β-amino carbonyl