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Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups

عنوان مقاله: Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups
شناسه ملی مقاله: JR_ORGC-5-1_003
منتشر شده در در سال 1398
مشخصات نویسندگان مقاله:

Ahmad Reza Massah - Departrment of Chemistry, Shahreza Branch, Islamic Azad University
Seyedeh Simin Dakhilpour - Department of Chemistry,Shahreza Branch, Islamic azad University,
Sara Ebrahimi - Department of Chemistry, Shahreza Branch, Islamic Azad University
Saeed Naseri - Department of Chemistry, Shahreza Branch, Islamic Azad University
Mina Nateghi - Department of Chemistry, Shahreza Branch, Islamic Azad University

خلاصه مقاله:
A series of interesting sulfonamides containing hydroxyl group were synthesized under solvent-free conditions. The synthetic route involves the selective reaction of amino alcohol and sulfonating agents. The sulfonamides were obtained by simple procedure after an easy work-up in high yield and purity, and characterized by IR, ۱H NMR and ۱۳C NMR analysis. These compounds were tested for antibacterial activity against four bacterium including Escherichia Coli, Staphylococcus Aurous, Bacillus Subtilis and Salemonella Typhi.

کلمات کلیدی:
Sulfonamide, Solvent-free, antibacterial, Amino alcohol

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1766212/