Akbar Mobinikhaledi - Chemistry Department, Arak University, Dr. Beheshti Ave, Arak, Iran
Naser Foroughifar - Faculty of Chemistry, Tehran North Branch, Islamic Azad University, Tehran, Iran
Hassan Moghanian - Department of Chemistry, Islamic Azad University-Dezful Branch, Dezful, Iran.
Hamid Reza Jaberi - Department of Chemistry, Faculty of Science, Arak University, Arak, Iran

Reaction of ۳,۴,۵,۶-tetrahydro-۲-pyrimidinethiol, prepared by cyclocondensation reaction of ۱,۳-diamino propane ۱ and carbon disulfide, with ethyl chloroacetate and substituted aromatic aldehydes in the presence of sodium acetate and acetic acid gave ۲-[(Z)-۱-(aryl)]-۶,۷-dihydro-۲H-isothiazolo[۲,۳-a]pyrimidine-۳(۵H)-one derivatives ۳(a-j) in good yields. ۱H-NMR spectroscopy, and elemental analysis were used for identification of these compounds.

Condensation, Pyrimidine, Isothiazole, Synthesis