Mir Rasul Mousavi - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴ Zahedan, Iran
Malek Taher Maghsoodlou - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴ Zahedan, Iran
Fatemeh Noori - Chemistry department of, The University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran
Nourallah Hazeri - Chemistry department of, The University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran

A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under ۸۰ °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely green and environmentally benign protocol for the preparation of tetrahydrobenzo[b]pyran derivatives.

sucrose, Malononitrile, Multi-component reactions (MCRs), Tetrahydrobenzo[b]pyran