Mehsa Bahram Shahri - Department of Pathology, Shahid Sadoughi Teaching Hospital, Yazd Medical School, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Saadat Eslami - MD, General Pathology, Department of Pathology, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran

Background: About ۴۰% of lymphomas occur in non-lymph nodes, most of which are in the digestive system. There are few studies on gastrointestinal lymphomas and their survival rate. Therefore, this study deals with the clinicopathological characteristics of gastrointestinal lymphomas in patients referred to the pathology ward of Shahid Sadoughi Hospital of Yazd, Iran, in ۲۰۱۶-۲۰۲۲. Method: This descriptive-cross-sectional study was conducted on patients with gastrointestinal lymphoma who referred to Shahid Sadoughi Hospital in Yazd, Iran, in ۲۰۱۶-۲۰۲۲. The factors of age, gender, type of lymphoma, and anatomical location were evaluated. The researchers collected the information after receiving the code of ethics by referring to the data archive department of Shahid Sadoughi Hospital in Yazd. The data were analyzed using SPSS software version ۱۶ and Chi-square and Fisher exact statistical tests. Results: In this study, ۲۹ patients were examined, of whom ۵۱.۲% (۱۶) were men, and the average age was ۴۹.۳ years. Based on the location of lymphoma, one case (۳.۴%) was in the rectum, four cases (۱۳.۸%) were in the small intestine, four cases (۱۳.۸%) were in the colon, and ۲۰ cases (۶۹%) were in the stomach. Diffuse large B cell lymphoma was the most frequent, with a frequency of ۱۸ cases (۶۲.۱%), followed by Maltoma, with six cases (۲۰.۷%). Abdominal pain, with a frequency of ۱۳ cases (۴۴.۸%), followed by weight loss, with a frequency of nine cases (۳۱%), was the most frequent. The frequency distribution of lymphoma types according to gender and anatomical location was insignificant. Conclusion: Gastrointestinal lymphomas are often B cell phenotypes, most of which are diffuse large cell types. The anatomical location of more than half of the tumors was in the stomach. Primary tumors of the gastrointestinal tract do not have specific clinical symptoms. These patients’ most frequent clinical symptoms were abdominal pain followed by B clinical symptoms (weight loss, weakness, and lethargy).

Diffuse Large B Cell Lymphoma, Maltoma, Gastrointestinal Tract