Seyed Mohammad Mohammadi - Endocrinologist, Internal Medicine Department of Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Golnaz Malekzadeh - Internal Medicine Resident, Internal Medicine Department of Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

The case-report is about a ۴۷ year old woman with adrenocorticotropin-independent macronudular adrenal hyperplasia (AIMAH), with is a rare cause of endogenous Cushing’s syndrome. Urin free cortisol (UFC) and cortisol of ۸AM were elevated along with the suppressed level of ACTH. Abdominal CT scan showed macronodules in both adrenals .The patient underwent left adrenalectomy and pathological data confirmed the diagnosis. The patient has been inhormon replacement therapy after surgery.

Macronodular adrenal hyperplasia, Cushing’s syndrome, Cortisol