Reyhane Azizi - Assistant Professor of Endocrinology, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Simin Manoochehry - Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Seyd Kazem Razavi-Ratki - Assistant Professor of Nuclear medicine, Department of Radiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Seyed Mostafa Seyed Hosseini - Assistant professor of Cardiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mahmoud Vakili - Associated Professor of Community Medicine, Health Monitoring Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nasim Namiranian - Assistant Professor of Community Medicine, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Objective: Blood group as a genetic trail can be associated with type ۲ diabetes. The aim of this research was to determine the distribution of ABO frequency and RH blood groups in type ۲ diabetic patients referred to Yazd diabetes center. Materials and Methods: In this research ۱۵۰۲ type ۲ diabetes patients of Yazd diabetes center were selected and checked for blood group ,age, sex, duration of diabetes, nephropathy, retinopathy ,diabetes control and familial history of diabetes. Data were analyzed on SPSS-۲۱. Results: From ۱۵۰۲ patients participated in this study ۹۹۵ were male (۶۶.۲%) and ۵۰۷ female (۳۳.۸%). The mean age (standard deviation) of patients was ۵۲±۱۰.۴۶. About ۵۴۱ participants (۳۶%) had O blood group, ۴۳۱ (۲۸%) A, ۳۷۹ (۲۵%) B, and ۱۵۰ (۱۰%) AB. About ۹۰.۸% patients were RH. The most frequency was observed in blood group O+ (۳۰.۹%) and the patients with blood group of AB- had the lowest frequency (۰.۵%) among patients. The various blood groups were not different in following subgroups; Familial History (P=۰.۶), diabetes duration (P=۰.۳۲), retinopathy (P=۰.۶۴), nephropathy (P=۰.۶۹), and hypertension (P=۰.۳۳). But HbA۱c<۷ and blood groups were significantly different (P=۰.۰۳). Discussion: The blood group O+ was the most frequent and AB- was the  least frequent among blood groups in this study .But for evaluation of  relationship between blood group and diabetes the prospective studies are suggested.

Diabetes, Blood group, ABO.