Ghasem Ahmadi Nasab - MA. Candidate in Exercise Physiology, Department of Sport Sciences, Education and Psychology Faculty, University of Sistan and Baluchestan, Zahedan, Iran
Reza Delavar - Assistant Professor, Department of Sport Sciences, Education and Psychology Faculty, University of Sistan and Baluchestan, Zahedan, Iran
Hamed Taheri - Assistant Professor of Internal Medicine, Cellular and Molecular Research center, Medical Science University of Zahedan, Zahedan, Iran

Objective: Renal failure is a complication of diabetes. It can be the risk factor of cardiovascular disease. This study aimed to evaluate the effect of exercise course and Aloe-Vera supplementation on renal function and lipid profile in type ۲ diabetes mellitus (T۲DM) patients. Materials and Methods: This is a clinical trial double blind with pre-test and post hoc test analyses with a control group. The studied population included a group of T۲DM diagnosed patients among whom ۲۴ men (۴۰-۶۰years) were selected voluntarily and purposefully and were classified into three groups by balanced block randomization method, exercise(E), exercise + supplement (E+S), and control (C), (n=۸/group). Combined exercise was planned in two ۱۲-minute repetitive sets with ۷۰% ۱RM. Then the participants ran for two ۱۰- minute sets with ۷۰-۷۵% maximum heart rate intensity on treadmill. E+S participants consumed ۵۰۰ mg/day Aloe Vera for ۶ weeks. Obtained data by SPSS-۱۹ software were analyzed using co-variance analysis method with Bonferroni post hoc test (P-value<۰/۰۵). Results: Results showed that E and E+S significantly improved GFR (P-value=۰.۰۱۱) and E with or without Aloe-Vera consumption decreased creatinine levels (P-value=۰.۰۴۲) and increased HDL levels (P-value˂۰.۰۰۱). The results demonstrated that LDL and TG levels showed no significant difference in reaction to the combined exercise and supplementation. Conclusion: Combined exercise along with Aloe-Vera supplementation has had significant effect on improving renal factors and lipid profile of T۲DM diagnosed patients

Combined exercise, Type ۲ diabetes, High density lipoprotein, Low density lipoprotein, Creatinine