Effects of medetomidine on intra-renal arteries resistive and pulsatility indices in clinically normal adult domestic shorthair cats

Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_VRFAN-9-2_006

تاریخ نمایه سازی: 25 آبان 1402

Abstract:

The aim of this study was to determine the effects of intramuscular injection of medetomidine on intra-renal arteriesresistive and pulsatility indices by duplex Doppler ultrasonographyin clinically normal adult domestic shorthair cats. For this purpose, twenty-six neutered adult healthy domestic shorthair cats (۱۳ females and ۱۳ males) were evaluated. B-mode, color Doppler and pulsed wave Doppler ultrasonography of right and left kidneys were performed to record the resistive index (RI) and pulsatility index (PI) of intra-renal arteries. To minimize statistical errors, the mean RI and PI were determined for each kidney by averaging three waveforms from the intra-renal arteries. Twenty-four hr later, the cats were sedated by ۰.۰۴ mg kg-۱ intramuscular administration of medetomidine. All the Doppler measurements were repeated ۱۵ min after drug administration. Mean ± standard deviation )SD( of PI and RI of the intra-renal arteries before administration of intramuscular medetomidine were ۱.۰۳ ± ۰.۰۸ and ۰.۶۱ ± ۰.۰۲, respectively. Fifteen min after medetomidine administration, the mean ± SD of PI and RI values were ۱.۰۴ ± ۰.۰۸ and ۰.۶۱ ± ۰.۰۲, respectively. Significant differences were not detected in mean PI and RI values before and ۱۵ min after drug administration. Our findings showed that intramuscular administration of medetomidine does not cause significant hemodynamic changes in the intra-renal arteries after ۱۵ min.

Authors

Farzaneh Azizi

Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

Mohammad Nasrollahzadeh Masouleh

Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

Seeyamak Mashhadi Rafie

Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

Ahmad Asghari

Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

Saied Bokaie

Department of Epidemiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

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