Leila Mousavi Seresht - Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Hamed Golmohamadzadeh - Department of Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Zohreh Yousefi - Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Amir Hosein Jafarian - Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Ali Moghimi - Department of Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Mojgan Soltani - Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Placental site trophoblastic tumor is a subtype of gestational trophoblastic neoplasm with unpredictable clinical behavior. Cytoreductive surgery is the cornerstone of treatment. The aim of this article is to present a case with an unusual site of metastases of placental site trophoblastic tumor. A ۳۵-year-old woman was referred to the academic center of GTN as a persistent case gestational trophoblastic neoplasm for standard treatment. Based on pancreatic metastases in the patient’s work-up, she underwent cytoreductive surgery that resulted in significant improvement in her condition. Proper surgical approach of placental site trophoblastic tumor has a major role in the remission of this disease.