Hamid Nasrollahi - Department of Radiation Oncology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Bita Geramizadeh - Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
Mansour Ansari - Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Seyed Hassan Hamedi - Department of Radiation Oncology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Mohammad Mohammadianpanah - Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Shapour Omidvari - Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Niloofar Ahmadloo - Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
Ahmad Mosalaei - Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran

Pineal region tumors are uncommon lesions in the central nervous system. Papillary tumor of the pineal region is recently recognized as a separate disease. Its incidence, treatment, and outcome are not well-defined. We have reported the case of a ۶ yearold- boy with papillary tumor of the pineal region. He presented with headaches, nausea and vomiting and, after a biopsy, was referred for radiotherapy. The patient received ۵۴ Gy irradiation to the pineal region followed by a chemotherapy regimen of cisplatin, vincristine, and lomostine. His tumor decreased slightly. After ۴ years, the patient has remained well and attends school. He is under routine follow-up. We suggest radical radiotherapy as the main treatment for papillary tumors of the pineal region.