Benyamin Rahmaty - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Kayvan Aghazadeh - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sasan Dabiri Satri - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Masoud Motassadi Zarandi - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ali Kouhi - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Nasrin Yazdani - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Reza Erfanian - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ardavan Tajdini - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Saeed Sohrabpour - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh Safi - Department of Radiology, Arak University of Medical Sciences, Arak, Iran.
Reza Shamsa - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Hamideh Ravand - Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Neda Jafari - Department of Radiology, Arak University of Medical Sciences, Arak, Iran.

Introduction:Idiopathic Sudden Sensorineural Hearing Loss as a subset of sensorineural hearing loss will be confirmed by a progressive hearing loss of at least ۳۰ dB at three contiguous frequencies over ۷۲ hours or less. A sudden or abrupt hearing loss correlates with the time course, and a vascular event is presumptive aetiology. There is an inverse association between Omega-۳ consumption and hearing loss. This study aimed to evaluate the efficacy of Omega-۳ adjunctive therapy in Idiopathic Sudden Sensorineural Hearing Loss by audiometric assessments.Materials and Methods:In this randomised, triple-blind, placebo-controlled trial, all participants aged ۱۸-۷۰ with a history of sudden deafness (within ۱۲ hours and ≤ ۳۰ days) were eligible for enrollment. They were included if audiology diagnostic tests confirmed the SSNHL. Ultimately, they were randomised to the Omega-۳ group and the placebo group.Results:Thirty-three patients were randomly allocated to the Omega-۳ group and thirty-two to the placebo group. Vertigo (۳۲.۳% of all patients) and underlying conditions had significant relationships with complete response (C.R.)-final hearing level ≤of ۲۵ dB in pure-tone average (P < ۰.۰۵). There was no significant difference between both groups before and after treatment. Although it was not statistically significant, patients in the Omega-۳ group had faster recovery than placebo.Conclusions:Omega-۳ adjunctive therapy did not have a therapeutic effect on SSNHL patients. Moreover, C.R. happened in half the patients. Vertigo and underlying conditions considerably worsen the recovery from SSNHL.

Omega-۳, Sudden sensorineural hearing loss (SSNHL), vertigo