Arezoo Ravanan - Ghadr Institute of Higher Education, Department of Pharmaceutical Chemistry, Koochesfahan, Guilan.
Nosrat O. Mahmoodi - Department of Chemistry, Faculty of Science, University of Guilan, P.O. Box ۴۱۳۳۵-۱۹۱۴, Rasht, Iran
Bahman Sharifzadeh - Department of Engineering Science and, Faculty of Engineering, East Guilan, University of Guilan, P.O. Box: ۴۱۹۳۸-۳۳۶۹۷, Iran
Fahimeh Majlesi - Ghadr Institute of Higher Education, Department of Pharmaceutical Chemistry, Koochesfahan, Guilan

Application of green chemistry for the synthesis of silver nanoparticles (AgNPs) using extracts of takes off of Ruta, Pimpinella saxifrage, and mango. And also a new method to reproduce new drugs based on silver nanoparticles with omeprazole and omeprazole sulfide and pantoprazole and pantoprazole sulfide with extricates of Ruta, Pimpinella saxifrage, and mango. In this investigation, the plant extricate was used to create natural silver nanoparticles. In this reaction, each drug was carried out with silver nitrate salt with a concentration of ۳۰ ml at room temperature, which changes the color of the compound from green to dark. In expansion, within the second step, silver nanoparticles were included within the narcotic, and an advanced metal nanoparticle from the plant extricates as a silver molecule reducer. The retention crest esteem is between ۴۰۰-۴۵۰ nm for the extricate and the color alters to dark compared to silver plasmon retention. FT-IR range appeared that drugs were effectively put on the surface of silver nanoparticles.

Omeprazole sulfide, Pantoprazole, Ruta, Pimpinella saxifrage, Green synthesis