Zahed Karimi-Jaberi - Department of Chemistry, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran

The remarkable ability of pyrazolo[۱,۲-b]phthalazines as a nitrogen-containing heterocycles with fused scaffold of bridgehead hydrazine and pyrazole moieties have generated substantial interest in the pharmaceutical industry and in the diversified field of synthetic chemistry. The present mini-review focuses on current progress in the synthesis of ۱H-pyrazolo[۱,۲‑b]phthalazine-۵,۱۰-dione derivatives using multi-component reaction of phthalhydrazide, aldehyde and malononitrile and covers publications from ۲۰۱۵ up to now.

Pyrazolophthalazine, Aldehyde, Malononitrile, Multi-component reaction, Heterocycle