Nazanin Shafie Pour - Department of Pharmaceutics, Mazandaran University of Medical Sciences, Sari, IR Iran
Majid Saeedi - Department of Pharmaceutics, Mazandaran University of Medical Sciences, Sari, IR Iran; ۲Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari, IR Iran
Katayoun Morteza Semnani - Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, IR Iran; ۴Complementary and Traditional Medicine Research Center, Mazandaran University of Medical Sciences, Sari, IR Iran
Jafar Akbari - Department of Pharmaceutics, Mazandaran University of Medical Sciences, Sari, IR Iran

Chronic ultraviolet exposure results in premature skin aging (photoaging), dyspigmentation, sallow color, textural changes, loss of elasticity, and premalignant actinic keratoses. UVB radiation is mainly responsible for acute damages such as sunburn, and long-term damage including melanoma. Today the sun's ultraviolet radiation (UVR) induced skin cancer is a major issue worldwide. History of sun exposure and sunburns are the most important behavioral risks. Childhood sun exposure is considered as a substantial risk because a child’s skin has a thinner stratum corneum, lower levels of protective melanin, and a higher surface area to body-mass-ratio. Thus, protection against UVR in childhood is essential. Research has shown that people who have had a sunburn in childhood or were in the sun unprotected are more likely to have skin cancer. In this article, we review the literature to address the protection of children against sun and skin cancer.

Sunlight, Infant, Ultraviolet Ray, Sun Protection Factor