Acute Generalized Exanthematous Pustulosis Due to Cephalexin: A Case Report and Literature Review

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
View: 40

This Paper With 6 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JPRE-9-3_009

تاریخ نمایه سازی: 9 آذر 1402

Abstract:

Introduction: Acute Generalized Exanthematous Pustulosis (AGEP) is a cutaneous reaction that may appear after using certain medications, such as cephalexin. This disease is characterized by non-follicular sterile pustules, erythematous, urticaria, fever over , and leukocytosis. Cephalexin belongs to the family of β-lactam antibiotics, which are widely used to treat infections. However, cephalexin skin sensitivities have been reported rarely. Herein, in this case, we aimed to report a patient presented with AGEP due to cephalexin usage.  Case Presentation: A ۱۲-year-old boy presented with warm skin lesions that gradually appeared on the limbs, trunk, face, and neck after using cephalexin powder on his left leg injury. Because of his symptoms, acetaminophen, fexofenadine hydrochloride, loxoprofen sodium, and ointment, including difluprednate and hydrocortisone, were prescribed. Over time, the patient’s fever subsided, and ۸ days later, the symptoms of AGEP, including urticaria, erythematous, and pustules in the neck and trunk, disappeared. Conclusions: Cephalexin is one of the antibiotics that doctors and patients consider when there is a possibility of infection. AGEP is a rare but severe reaction that can manifest as skin rashes in any age and sex following the use of cephalexin, so the patient should be careful when using this antibiotic.

Keywords:

Acute generalized exanthematous pustulosis , Cephalexin , Adverse drug reaction

Authors

Hamed Jafarpour

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Mahdie Sadat Mousavi

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Shirin Sheibani

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Javad Ghaffari

Department of Pediatrics, School of Medicine, Pediatric Infectious Diseases Research Center, Bu-Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran.

Abbas Dabbaghzadeh

Department of Pediatrics, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Salar Behzadnia

Department of Pediatrics, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Lockwood SJ, Saavedra AP. Chapter ۶ - Cutaneous Reactions to ...
  • Beylot C, Bioulac P, Doutre MS. [Acute generalized exanthematic pustuloses ...
  • Abbasi M, Mirderikvand F, Adavi H, Hojati M. The relationship ...
  • Mohaghegh F, Jelvan M, Rajabi P. A case of prolonged ...
  • Halevy S. Acute Generalized Exanthematous Pustulosis. In: Shear NH, Dodiuk-Gad ...
  • Saissi EH, Beau-Salinas F, Jonville-Bera AP, Lorette G, Autret-Leca E. ...
  • DaCunha M, Moore S, Kaplan D. Cephalexin-induced acute generalized exanthematous ...
  • Holscher CM, Mauck SK, Armstrong L, Buchanan JA. Man with ...
  • Chaudhry SB, Veve MP, Wagner JL. Cephalosporins: A Focus on ...
  • Griffith RS. The pharmacology of cephalexin. Postgraduate medical journal. ۱۹۸۳;۵۹ ...
  • Murray KM, Camp MS. Cephalexin-induced Stevens-Johnson syndrome. The Annals of ...
  • Arroyo MP, Heller P, Pomeranz MK. Generalized pustules in a ...
  • Abbas M, Holfeld K, Desjardins D, Zimmer J. Pustular psoriasis ...
  • Feldmeyer L, Heidemeyer K, Yawalkar N. Acute Generalized Exanthematous Pustulosis: ...
  • Kley C, Murer C, Maul JT, Meier B, Anzengruber F, ...
  • نمایش کامل مراجع