The Relationship Between Serum Uric Acid and Cardiometabolic Risk Factors in Iranian Children and Adolescents

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نوع سند: مقاله ژورنالی
زبان: English
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JR_JPRE-9-2_011

تاریخ نمایه سازی: 9 آذر 1402

Abstract:

Context: There has been an increasing interest in epidemiological and clinical studies concerning the role of uric acid in cardiometabolic diseases, especially in children and adolescents. However, these potential relationships remain undiscovered; accordingly, its pathophysiological mechanisms remain unrecognized. This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents.  Objectives: This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Methods: The data of ۵۹۵ individuals aged ۷-۱۸ years were assessed in this research. Anthropometric measurements and laboratory tests were performed according to standardized protocols. Results: The Mean±SD age of the ۵۹۵ explored students was ۱۲.۳۹±۳.۰۷ years. The overall Mean±SD SUA level of the study participants was measured as ۴.۲۲±۱.۱۳ mg/dL, with significant gender-wise differences (۴.۰۴±۰.۹۷ mg/dL vs ۴.۳۸±۱.۲۴ mg/dL, respectively; P<۰.۰۵). The prevalence of hyperuricemia based on the ۹۰th percentile of SUA levels was equal to ۱۰.۶%. There was a positive association between SUA levels and abdominal obesity (waist circumference: ≥۹۰th percentile) [Odds Ratio (OR): ۱.۵۴; ۹۵% Confidence Interval (CI): ۱.۲۶ to ۱.۸۶] and general obesity [gender-specific Body Mass Index (BMI) for >۹۵th percentile] (OR: ۲.۳۲; ۹۵% CI: ۱.۷۴ to ۳.۱۱). Conclusions: This study suggested BMI and waist circumference as cardiometabolic risk factors, i.e. significantly associated with SUA levels in children and adolescents.

Authors

Motahar Heidari-Beni

Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Roya Riahi

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Fatemeh Mohebpour

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Majid Khademian

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Roya Kelishadi

Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

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  • Özalp Kızılay D, Şen S, Ersoy B. Associations Between Serum ...
  • Fu S, Luo L, Ye P, Xiao W. Epidemiological associations ...
  • Khan A, Shah MH, Khan S, Shamim U, Arshad S. ...
  • Bassols J, Martínez-Calcerrada JM, Prats-Puig A, Carreras-Badosa G, Díaz-Roldán F, ...
  • Scheepers LE, Boonen A, Pijnenburg W, Bierau J, Staessen JA, ...
  • Sharaf El Din UAA, Salem MM, Abdulazim DO. Uric acid ...
  • Borghi C, Palazzuoli A, Landolfo M, Cosentino E. Hyperuricemia: a ...
  • Xiong Q, Liu J, Xu Y. Effects of Uric Acid ...
  • Motlagh ME, Ziaodini H, Qorbani M, Taheri M, Aminaei T, ...
  • WHO Child Growth Standards based on length/height, weight and age. ...
  • Moulin-Mares SRA, Oliosa PR, Faria ER, Zago-Gomes MP, Mill JG. ...
  • Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. ...
  • Petrikova J, Janicko M, Fedacko J, Drazilova S, Madarasova Geckova ...
  • Ndrepepa G. Uric acid and cardiovascular disease. Clinica chimica acta; ...
  • Lee SJ, Oh BK, Sung KC. Uric acid and cardiometabolic ...
  • Cortese F, Scicchitano P, Meliota G, Giordano P, Ciccone MM. ...
  • Sun D, Li S, Zhang X, Fernandez C, Chen W, ...
  • Chen Q, Yin YJ, Chen WY, Wu JN, Huang X. ...
  • Ford ES, Li C, Cook S, Choi HK. Serum concentrations ...
  • Li N, Zhang S, Li W, Wang L, Liu H, ...
  • Cardoso AS, Gonzaga NC, Medeiros CC, Carvalho DF. Association of ...
  • King C, Lanaspa MA, Jensen T, Tolan DR, Sánchez-Lozada LG, ...
  • Grayson PC, Kim SY, LaValley M, Choi HK. Hyperuricemia and ...
  • Ishizaka N, Ishizaka Y, Toda A, Tani M, Koike K, ...
  • Lurbe E, Torro MI, Alvarez-Pitti J, Redon J, Borghi C, ...
  • Song C, Zhao X. Uric acid promotes oxidative stress and ...
  • Kubota M. Hyperuricemia in Children and Adolescents: Present Knowledge and ...
  • Wang Y, Hu JW, Lv YB, Chu C, Wang KK, ...
  • Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, ...
  • Cicero AF, Rosticci M, Bove M, Fogacci F, Giovannini M, ...
  • Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, ...
  • Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular ...
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