Ali Alizadeh Khatir - Department of Neurology, Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Seyed Mohammad Masood Hojjati - Department of Neurology, Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Alijan Ahmadi Ahangar - Department of Neurology, Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Hoda Naghshineh - Department of Neurology, Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Payam Saadat - Department of Neurology, Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Multiple sclerosis (MS) is one of the most important debilitating diseases in which the myelin sheaths of nerve cells in the brain and spinal cord are damaged. In this review, we aimed to review the pathophysiology of MS. This impairment causes ability disorder of the parts of the nervous system which are responsible for communication, leading to different symptoms including physical and psychological problems. This study was conducted through a Narrative review using keywords including Multiple Sclerosis, Epidemiology through Search in International Scientific Databases, including: PubMed, Web of Science, Google Scholar and Scopus, and Persian scientific databases including: Barakatkns Knowledge System, Academic Jihad Database, Iranian Medical Library (Medlib), Magiran Database, Knowledge Reference (Civilica), and a search was done on the World Health organization website. In this review study, using keywords such as "pathophysiology" and "multiple sclerosis".

Multiple Sclerosis, Pathophysiology, Nervous system