Samareh Mortazavi - Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran- Assistant Professor, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences,
Atessa Pakfetrat - Professor, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Masoome Baghbani - Private Dental Practice, Mashhad, Iran
Atie Safaee - Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran- Assistant Professor, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences,

Background: The aim of this study was to evaluate the radiographic and clinical features of malignant oral and maxillofacial lesions in patients referred to the Radiology Department of Mashhad Dental School from ۲۰۰۳ to ۲۰۱۷. Methods: A total of ۴۵ radiographs of patients who had been referred to the Radiology Department of Mashhad Dental School from ۲۰۰۳ to ۲۰۱۷ were selected from the radiology archive. The patients presenting with malignant lesions in jaws and a definite pathologic diagnosis were selected as the study population. The radiographic features of lesions were investigated using intraoral radiographies, panoramic, and cone-beam computed tomography (CBCT) or computed tomography (CT) views. Then, ۱۸ patients whose information was available were evaluated. Fisher’s exact test was used to compare the characteristics of lesions. Results: The age of the patients ranged from ۵ to ۸۴ years, with a mean of ۴۹.۱۸ years. Of the ۴۵ lesions identified, squamous cell carcinoma (SCC) was the most prevalent malignancy, followed by lymphoma and mucoepidermoid carcinoma. Most malignant lesions were seen in the posterior region of the jaws, and lesions were generally more prevalent in the mandible. Additionally, ۷۷.۸% of the observed malignancies had an ill-defined border, and ۸۶.۶% of them were radiolucent. In the clinical view, swelling was the most common symptom, and the duration of the disease in the majority of the lesions was less than ۳ months. Conclusions: Paying attention to the course of the lesion, its internal structure and borders in the radiographic view can lead to a more accurate differentiation of malignant lesions from benign ones and timely referral of the patient.

Diagnosis, Differential, Mandibular neoplasms, Diagnostic imaging, Maxillary neoplasms, Radiography