Patterns of Intravenous Human Immunoglobulin Administration in a Middle Eastern Teaching Hospital
عنوان مقاله: Patterns of Intravenous Human Immunoglobulin Administration in a Middle Eastern Teaching Hospital
شناسه ملی مقاله: JR_AJPR-3-1_001
منتشر شده در در سال 1402
شناسه ملی مقاله: JR_AJPR-3-1_001
منتشر شده در در سال 1402
مشخصات نویسندگان مقاله:
Yasim Zabihi - Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Etminaniesfahani - Department of Clinical Pharmacy, Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Rangchian - Department of Clinical Pharmacy, Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
خلاصه مقاله:
Yasim Zabihi - Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Etminaniesfahani - Department of Clinical Pharmacy, Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Rangchian - Department of Clinical Pharmacy, Pharmacy School, Hamadan University of Medical Sciences, Hamadan, Iran
Background: Drug use evaluation (DUE) helps to investigate and modify the pattern of drug administration
with the aim of improving patient care and cost saving. Considering the important indications for
intravenous immunoglobulin (IVIG) and its high cost, assessment of its prescription pattern could be
helpful in increasing the efficiency of the health system.This study aimed to investigate the pattern of IVIG
use in a tertiary teaching hospital.
Methods: This retrospective study included all inpatients who received IVIG in spring and summer ۲۰۲۰.
The needed information was extracted from patients’ files. Data were analyzed using SPSS and compared
with the standard guidelines.
Results: A total of ۷۲ patients received IVIG. The indications were “FDA-approved” and “CEDITacknowledged”
in ۳۳.۳% and ۶۱.۱% of the cases, respectively, and ۴۵.۸% adhered to the “red” indications
of the UK protocol. Moreover, all prescriptions were in accordance with the approved indications of
the FDO (Iranian Food and Drug Organization) guideline. Guillain-Barré syndrome (GBS), chronic
inflammatory demyelinating polyneuropathy, and COVID-۱۹ were the three most common causes of IVIG
administration. Additionally, ۶۶.۷% had received the recommended dose regimen and ۵۱.۳% experienced
drug side effects requiring some measures.
Conclusion: The occurrence of adverse drug reactions in more than half of the studied patients and related
costs substantiate the need for enhancing physicians’ refrain from the unnecessary prescription of the IVIG,
nursing staff’s knowledge, and the inclusion of a clinical pharmacist in the healthcare team.
کلمات کلیدی: IVIG, Immune globulin, DUE, Drug use evaluation, Rational prescription
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1841442/