Anggun Selvya Arsyad - Master of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Sleman ۵۵۲۸۱, Yogyakarta, Indonesia
Arief Nurochmad - Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Sleman ۵۵۲۸۱, Yogyakarta, Indonesia
Nanang Fakhrudin - Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Sleman ۵۵۲۸۱, Yogyakarta, Indonesia- Medicinal Plants and Natural Products Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Sleman

Ficus elastica Roxb. ex Hornem is usually found in tropical and subtropical areas, used in traditional medicine for various health problems, including pain, rheumatism, diarrhea, hypertension, infection, skin allergies, anemia, wound, hernia, and hemorrhoids. This review aims to present the phytoconstituents and pharmacological activities of F. elastica. A literature search employing PubMed, Google Scholar, Semantic Scholar, and Library was done to retrieve the relevant articles. F. elastica is a good source of traditional medicine for the treatment of various types of diseases, especially for microbial infections and preeclampsia. Quercitrin and myricetrin, having strong antioxidant activity, as well as ficusamide, ficusoside B, elastiquinone, elasticoside, and elasticamide are compounds, which have potential to be developed as new drugs for these conditions. In sum, the data regarding the pharmacological and safety aspects of this plant and its components are still limited. However, F. elastica is a natural product that has beneficial to human health and might be a good source for the preparation of new drugs.

Rubber tree, Herbal medicine, Secondary metabolites, Biological activities Phytoconstituent