Sasan Ghaffari - Department of Science and Technology, Supreme National Defense University, Tehran, Iran- Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran- Research Center for New Technologies in Life Science
Hanif Kazerooni - Department of Science and Technology, Supreme National Defense University, Tehran, Iran
Amir Salehi-Najafabadi - Research Center for New Technologies in Life Science Engineering, University of Tehran, Tehran, Iran- Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran

The novel coronavirus disease ۲۰۱۹ (COVID-۱۹) still poses a serious threat to every human on the planet nearly ۱.۵ years after its beginning. Unfortunately, the current diagnostic methods, although highly sensitive and specific, still suffer from many shortcomings. Faster and easy-to-operate diagnostic systems are undoubtedly sorely needed. The CRISPR/Cas platform has gained much attention in recent years in a wide range of biomedical sciences. Besides its treatment potential and drug and vaccine development, it can be used for disease diagnosis. Thus, the CRISPR/Cas-based system holds great promise for providing a rapid and easily deployable COVID-۱۹ detection and is on par with the conventional diagnostic approaches in terms of sensitivity and specificity. In this review article, we discuss the latest advances of CRISPR/Cas technology as a fast and reliable severe acute respiratory syndrome coronavirus ۲ (SARS-CoV-۲) detection method.

COVID-۱۹, SARS-CoV-۲, Diagnosis, CRISPR