Association of air pollutants and genetic polymorphism on the initiation of atherosclerosis

Publish Year: 1391
نوع سند: مقاله کنفرانسی
زبان: English
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CANPM01_064

تاریخ نمایه سازی: 13 اسفند 1391

Abstract:

The harmful effects of air pollution on atherosclerotic cardiovascular diseases (ACVD) are well-documented;[1] even short-term exposure to air pollutants isassociated with cardiovascular disorder.[2,3] The underlying mechanisms have yet to be determined; pulmonary and systemic oxidative stress and inflammatoryresponses provoking endothelial dysfunction, disturbance of the platelet function, blood coagulability, andthrombosis are suggested to be the effects of air pollutants.[4,5] Some experimental studies have confirmed the possible effect of air pollutants on the blood vesselendothelium and in turn on increasing the risk of atherosclerosis.[6-

Authors

Parinaz Poursafa

MSc of Environmental Engineering, Environment Research Center, Isfahan University of Medical Sciences

Mohammad Mehdi Amin

Assistant Professor of Environmental Health Engineering, Environment Research Center, Isfahan University of Medical Sciences

Roya Kelishadi

Professor of pediatrics, Child Growth and Development Research Center, Isfahan University of Medical Sciences

Shaghayegh Haghjoo Javanmard

Department of Physiology, Applied Physiology Research Center,Isfahan University of Medical Sciences

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