Azadeh Zareie - Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad Bagherniya - Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Anesthesia and
Amir Hossein Sahebkar - Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Polish Mother&#۰۳۹;s Memorial
Manoj Sharma - Environmental & Occupational Health, School of Public Health, University of Nevada, Las Vegas, NV, USA
Fariborz Khorvash - Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran
Akbar Hasanzadeh - Departments of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
Gholamreza Askari - Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Anesthesia and

Objective: Increased body mass index (BMI) seems to be a risk factor for migraine attacks. Cinnamon has anti-inflammatory, neuroprotective, and anti-obesity effects. This study aimed to assess the effects of cinnamon on anthropometric indices and headache-related disability of patients with migraine.Materials and Methods: This study was conducted as a randomized, double-blind, placebo-controlled trial involving ۵۰ migraine patients. Patients were randomized to receive either ۶۰۰ mg cinnamon powder or placebo capsules for two months. Height, body weight (BW), waist circumference (WC), and hip circumference (HC) were measured.Furthermore, Minimal or Infrequent Disability (MIDAS) and Headache Daily Result (HDR) Questionnaires were recorded.Results: At the end of the treatment period, BW and BMI did not change in the intervention group; however, both factors were significantly increased in the placebo group (p=۰.۰۰۱). The change of WC, HDR and MIDAS was significantly different between the intervention and placebo groups (p<۰.۰۰۱). Furthermore, HC and WHR significantly decreased (p=۰.۰۰۱).Conclusion: Cinnamon seems to have beneficial effects on anthropometric indices and headache disability of migraine patients.

Cinnamon, Migraine, Anthropometry, Headache, Weight