Ayat Arjmand - Department of Physical Education and Sport Sciences, Faculty of Human Science, Mahallat Branch, Islamic Azad University, Mahallat, Iran.
Bahram Abedi - Department of Physical Education and Sport Sciences, Faculty of Human Science, Mahallat Branch, Islamic Azad University, Mahallat, Iran.
Seyed Ali Hosseini - Department of Sport Physiology, Faculty of Human Science, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.

Background: Consumption of anabolic steroids causes damage to various tissues, including the heart.  Objectives: This study aimed to investigate the effect of Resistance Training (RT) on Malondialdehyde (MDA) and Protein Carbonyl (PC) in the heart tissue of rats exposed to stanozolol (S). Methods: In this experimental study, ۱۸ rats with the mean age of ۸ weeks and weight range of ۱۵۰ to ۲۰۰ g were selected and divided into three groups of ۶ rats: ۱. Sham (normal saline consumption) (Sh), ۲. S, and ۳. S+RT. For ۸ weeks, the S and S+RT groups received ۵ mg/kg/d S, and the S+RT group performed ۵ RT sessions per week. Measurement of MDA and PC in the heart tissue was performed with the enzyme-linked immunosorbent assay. Results: Stanozolol had a significant effect on increasing MAD (P=۰.۰۰۱) and PC (P=۰.۰۳) in the heart tissue. However, RT led to a decrease in MDA and PC in the heart tissue of rats exposed to S (P=۰.۰۰۱). Conclusion: It appears that S consumption leads to an increase in MDA and PC levels in the heart tissue, while RT can improve the elevated levels of MDA and PC.

Malondialdehyde, Protein carbonyl, Resistance training, Stanazolol, Heart