Fariba Heidarizadeh - Department of Chemistry, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Farangis Sistani - Department of Chemistry, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran

This project highlights the significance of oxazolidin-۲-ones, a vital class of five-membered heterocyclic compounds renowned for their medicinal properties and uses as chiral auxiliary compounds. To facilitate the synthesis of oxazolidin-۲-one derivatives, a novel approach employing acidic nanoparticles was employed. Specifically, a magnetic solid acid catalyst comprising sulfonic acid, stabilized on manganese ferrite nanoparticles with a chitosan coating (MnFe۲O۴@CS@SO۳H), was meticulously developed and characterized through various techniques. These nanoparticles exhibit remarkable thermal stability and can be effortlessly isolated from the reaction medium using a magnetic field owing to their inherent magnetic properties. Notably, analysis of FE-SEM images reveals the nanoparticles' uniform and spherical morphology, with a size scale in the nanometer range. This innovative catalyst promises to significantly enhance the efficiency of oxazolidin-۲-one derivatives synthesis in chemical and pharmaceutical industries.

Acid Catalyst, Carbamate, Medicinal chemistry, Nano Catalyst, oxazolidin-۲-one derivatives