M J Tahmasebi Birgani - Department of Radiation Oncology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
N Chegeni - Department of Medical Physics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
F Farhadi Birgani - Department of Medical Physics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
D Fatehi - Department of Medical Physics, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
Gh Akbarizadeh - Department of Electrical Engineering, Faculty of Engineering, Shahid Chamran University of Ahvaz, Ahvaz, Iran
A Shams - Department of Radiation Oncology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Background: One of the leading causes of death is brain tumors. Accurate tumor classification leads to appropriate decision making and providing the most efficient treatment to the patients. This study aims to optimize brain tumor MR images classification accuracy using optimal threshold, PCA and training Adaptive Neuro Fuzzy Inference System (ANFIS) with different repetitions. Material and Methods: The procedure used in this study consists of five steps: (۱) T۱, T۲ weighted images collection, (۲) tumor separation with different threshold levels, (۳) feature extraction, (۴) presence and absence of feature reduction applying principal component analysis (PCA) and (۵) ANFIS classification with ۰, ۲۰ and ۲۰۰ training repetitions. Results: ANFIS accuracy was ۴۰%, ۸۰% and ۹۷% for all features and ۹۷%, ۹۸.۵% and ۱۰۰% for the ۶ selected features by PCA in ۰, ۲۰ and ۲۰۰ training repetitions, respectively. Conclusion: The findings of the present study demonstrated that accuracy can be raised up to ۱۰۰% by using an optimized threshold method, PCA and increasing training repetitions.

MRI, Brain Tumor Detection, ANFIS, PCA, Training Repetition