Hootan Manhoobi - Department of Cardiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi Sheibani - Department of Cardiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maryam Taherkhani - Department of Cardiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Saeid Shahraz - Tufts Medical Center, Boston, MA, United States.
Mohammad Reza Beyranvand - Department of Cardiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Introduction: Pathological Q waves in an electrocardiogram (ECG) are robust prognostic markers in patients with ST-segment elevation myocardial infarction (STEMI), a leading global cause of death. Accurately identifying high-risk patients with STEMI is essential to provide tailored management, thereby improving patient outcomes. Thus, this study aims to evaluate the relationship between the number of leads with pathological Q wave in the first ECG and left ventricular ejection fraction (LVEF) before discharge.Methods: This retrospective study reviewed the records of ۱۵۲ STEMI patients meeting inclusion criteria at Taleghani Hospital from April ۲۰۱۴ to August ۲۰۱۸. The initial ECGs, angiography, and echocardiography data were extracted, read by cardiologists, and prepared for analysis.Results: The majority of patients (۸۷.۵%) were males, and ۶۹.۷% had a pathological Q wave at the first ECG. The median of LVEF was significantly lower in patients with a pathological Q wave than in patients without a pathological Q wave (۴۵ versus ۵۰, p-value < ۰.۰۰۱). In addition, there was a mild negative correlation between the number of pathological Q waves and LVEF (r = -۰.۳۱۸, p-value < ۰.۰۰۱).Conclusions: This study reveals the presence of a mild negative linear relationship between LVEF and the number of pathological Q waves in STEMI patients.

Stroke Volume, ST Elevation Myocardial Infarction, Electrocardiogram, echocardiography