Correlation of heart rate response to dipyridamole stress during SPECT myocardial perfusion imaging with clinical factors

Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
View: 61

This Paper With 7 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_IRJNM-32-1_006

تاریخ نمایه سازی: 8 بهمن 1402

Abstract:

Introduction: Myocardial perfusion imaging (MPI) with pharmacologic stress is a useful technique for evaluation of suspected coronary artery disease (CAD). Heart rate responses (HRR) to vasodilators such as dipyridamole mirror autonomic activity and may provide important prognostic information in CAD patients. In this study, the impact of baseline characteristics of patients including age and gender on the expected HRR has been assessed.Methods: This retrospective study included database of ۲۵۸۴ patients (۱۵۷۵ female, ۱۰۰۹ male) who were referred to the nuclear medicine department for pharmacologic MPI. The HRR to dipyridamole was calculated as ratio of maximal heart rate (HR) during or shortly after dipyridamole infusion to baseline HR. The association of HRR with age, gender, presence of other known CAD risk factors and perfusion findings was evaluated.Results: Significant correlation was found between HRR and sex, age, diabetes mellitus (DM), hypertension (HTN), and chronic kidney disease (CKD) (P < ۰.۰۰۱) in both univariate and multivariate analysis. The mean HRR was also significantly higher in patients with normal perfusion on SPECT MPI as compared to patients with abnormal findings, however, multivariate regression analysis showed no significant correlation. In the subgroup of patients with no CAD risk factors, HRR was significantly higher in women under age ۵۵ years.Conclusion: The HRR during dipyridamole infusion depends on age and gender, irrespective of presence of other CAD risk factors and should be considered in the interpretation of. Besides, DM, HTN and CKD are also correlated with lower HRR to dipyridamole stress.

Authors

Fatemeh Maleki

Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Tahereh Ghaedian

Department of Nuclear Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • The role of myocardial perfusion SPECT in short-term cardiac prognosis of end-stage renal disease [مقاله ژورنالی]
  • Tajik Rostami M, Mirshahvalad SA, Familrashtian S, Ghanbari H, Dehghani ...
  • Leppo JA. Dipyridamole myocardial perfusion imaging. J Nucl Med. ۱۹۹۴ ...
  • Hellsten Y, Nyberg M, Jensen LG, Mortensen SP. Vasodilator interactions ...
  • Hage FG, Heo J, Franks B, Belardinelli L, Blackburn B, ...
  • AlJaroudi W, Campagnoli T, Fughhi I, Wassouf M, Ali A, ...
  • Bravo PE, Hage FG, Woodham RM, Heo J, Iskandrian AE. ...
  • Hage FG, Dean P, Iqbal F, Heo J, Iskandrian AE. ...
  • Hage FG, Perry G, Heo J, Iskandrian AE. Blunting of ...
  • Abidov A, Hachamovitch R, Hayes SW, Ng CK, Cohen I, ...
  • Johnston DL, Hodge DO, Hopfenspirger MR, Gibbons RJ. Clinical determinants ...
  • Clarke B, Conradson TB, Dixon CM, Barnes PJ. Reproducibility of ...
  • Homma S, Gilliland Y, Guiney TE, Strauss HW, Boucher CA. ...
  • Rongen GA, Brooks SC, Pollard MJ, Ando S, Dajani HR, ...
  • Conradson TB, Clarke B, Dixon CM, Dalton RN, Barnes PJ. ...
  • Aksut SV, Pancholy S, Cassel D, Cave V, Heo J, ...
  • Ogilby JD, Iskandrian AS, Untereker WJ, Heo J, Nguyen TN, ...
  • La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, ...
  • Gupta A, Wang Y, Spertus JA, Geda M, Lorenze N, ...
  • Izadnegahdar M, Singer J, Lee MK, Gao M, Thompson CR, ...
  • Lehto HR, Lehto S, Havulinna AS, Ketonen M, Lehtonen A, ...
  • Nabel EG. Heart disease prevention in young women: sounding an ...
  • Vaccarino V, Badimon L, Corti R, de Wit C, Dorobantu ...
  • Lee KH, Yoon JK, Lee MG, Lee SH, Lee WR, ...
  • Gerritsen J, Dekker JM, TenVoorde BJ, Kostense PJ, Heine RJ, ...
  • Maser RE, Mitchell BD, Vinik AI, Freeman R. The association ...
  • O'Brien IA, McFadden JP, Corrall RJ. The influence of autonomic ...
  • Valensi P, Sachs RN, Harfouche B, Lormeau B, Paries J, ...
  • نمایش کامل مراجع