Folic Acid as an Exploiter of Natural Endocytosis Pathways in Drug Delivery

Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_CHM-8-2_003

تاریخ نمایه سازی: 14 بهمن 1402

Abstract:

The use of polymers modified with folic acid in drug delivery to treat many diseases has long captivated the attention of scientists. Given the distinctive characteristics of folic acid in the realms of food, pharmaceuticals, and chemicals, this review explores the methods employed in bonding folic acid to diverse polymers through the lens of organic synthesis. Furthermore, it examines the behavior of folic acid that has been conjugated to different polymers in drug delivery, along with the interaction between folic acid and folate acceptors. It is important to acknowledge that the articles employed in this review span the years ۲۰۰۲ to ۲۰۲۳.

Authors

Asrin Bahmani

Department of Medicinal Chemistry, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

Alireza Taghvaei

Department of Medicinal Chemistry, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

Farzin Firozian

Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran

Gholamabbas Chehardoli

Department of Medicinal Chemistry, School of Pharmacy, Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

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