The effects of green tea extract on teratogenicity induced by low frequency electromagnetic field on bone marrow Balb/C mice embryo
عنوان مقاله: The effects of green tea extract on teratogenicity induced by low frequency electromagnetic field on bone marrow Balb/C mice embryo
شناسه ملی مقاله: JR_HERM-3-1_009
منتشر شده در در سال 1393
شناسه ملی مقاله: JR_HERM-3-1_009
منتشر شده در در سال 1393
مشخصات نویسندگان مقاله:
Javad Baharara
Saeedeh Zafar Balanejad
Esmat Kamareh
Majid Asadi-Samani
خلاصه مقاله:
Javad Baharara
Saeedeh Zafar Balanejad
Esmat Kamareh
Majid Asadi-Samani
Introduction: Electromagnetic fields produce free radicals which might be teratogen. Camellia sinensis is rich in natural antioxidants and antioxidants can neutralize free radicals effects. In present research the effect of C. sinensis extract in reduction of teratogenicity induced by electromagnetic field with ۵۰ gauss intensity was studied on bone marrow of Balb/C mice fetuses. Methods: In this experimental study, ۲۴ Balb/C pregnant mice were randomly divided into four groups: control, sham exposed (off position), experimental ۱ (electromagnetic field with ۵۰-gauss intensity) and experimental ۲ (treatment by C. sinensis extract + electromagnetic field with ۵۰-gauss intensity). After treatment period, the bone marrow aspirates of Balb/C mice embryos were prepared and studied by Giemsa. The quantitative data were analyzed by Kruskal-Wallis and Kolmogorov- Smirnov using SPSS۱۶ software at the level of p<۰.۰۵. Results: The mean number of promyelocytes, myelocytes, erythrocytes, necrotic and apoptotic cells in experimental group۱ compared with sham exposed embryos showed significant increase but the mean number of eosinophils in experimental group ۱ compared with sham exposed embryos showed significant decrease. The mean number of promyelocyte and erythrocyte in experimental group ۲ compared with experimental group ۱ showed significant decrease. The mean of necrotic and apoptotic cells, in experimental group ۲ compared with experimental group ۱ showed significant increase. Conclusion: Usage of C. sinensis can decrease the damage due to teratogenicity induced by low frequency electromagnetic field in some cells.
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1910887/