Mohammad Reza Jamalpour
Arash Dehghan
Reza Nadripour
Faryad Fatehi
Hossein Nahidfar
Hamid Naderi

Mucoepidermoid carcinoma (MEC) can be found as a primary intraosseous lesion, accounting for ۲-۳% of head and neck MEC. The mandibular premolar-molar region is the most common site, up to ۵۰% of which is associated with dental cysts and/or impacted teeth. Histopathologically, it is classified into low, intermediate, and high grades. The best modality of treatment for intraosseous MEC is radical surgical resection. Radiotherapy is recommended to improve the prognosis in patients with positive margins, positive node disease, and moderate- and high-grade lesions. This paper reports a rare case of intraosseous MEC of the mandible in a ۱۷-year-old female, discovered after the panoramic radiography of the jaws and treated by the segmental resection of the mandible through transoral approach and adjuvant radiotherapy.